1. What is the Evolution Frequency Equation?

The evolution frequency equation calculates how allele frequencies change over generations under selection pressure. It models how advantageous alleles increase in frequency in a population.

2. How Does the Calculator Work?

The calculator uses the evolution equation:

Where:

• \( F \) — Final allele frequency (dimensionless)
• \( F0 \) — Initial allele frequency (dimensionless)
• \( s \) — Selection coefficient (dimensionless)
• \( t \) — Number of generations (dimensionless)

Explanation: The equation shows how an allele with selection advantage 's' changes frequency over 't' generations starting from initial frequency F0.

3. Importance of Frequency Calculation

Details: Understanding allele frequency changes helps predict evolutionary trajectories, assess genetic drift, and model population genetics.

4. Using the Calculator

Tips: Enter initial frequency (0-1), selection coefficient (can be positive or negative), and number of generations. All values must be valid.

5. Frequently Asked Questions (FAQ)

Q1: What does the selection coefficient represent?
A: The selection coefficient (s) represents the relative fitness advantage (s > 0) or disadvantage (s < 0) of an allele.

Q2: What are typical values for selection coefficients?
A: Most selection coefficients in nature are small, typically between -0.1 and 0.1, though stronger selection can occur.

Q3: Does this model account for genetic drift?
A: No, this simple model only accounts for selection. More complex models incorporate drift and other factors.

Q4: What if the frequency exceeds 1?
A: The calculator caps frequencies at 1 (100%), as frequencies cannot biologically exceed this value.

Q5: Can this be used for recessive alleles?
A: This simple model works best for dominant or additive alleles. Recessive alleles require more complex modeling.