1. What is the Evolution Frequency Equation?

The evolution frequency equation calculates how allele frequencies change over time under selection pressure. It models how an allele's frequency (F) changes from its initial frequency (F0) based on selection coefficient (s) over (t) generations.

2. How Does the Calculator Work?

The calculator uses the evolution frequency equation:

Where:

• \( F \) — Current allele frequency (dimensionless)
• \( F_0 \) — Initial allele frequency (dimensionless)
• \( s \) — Selection coefficient (dimensionless)
• \( t \) — Number of generations (dimensionless)
• \( e \) — Base of natural logarithm (~2.71828)

Explanation: The equation models how allele frequencies change exponentially under constant selection pressure over multiple generations.

3. Importance of Frequency Calculation

Details: Tracking allele frequency changes helps predict evolutionary trajectories, understand selection pressures, and model population genetics scenarios.

4. Using the Calculator

Tips: Enter initial frequency (0-1), selection coefficient (can be positive or negative), and number of generations. All values must be valid.

5. Frequently Asked Questions (FAQ)

Q1: What does a positive selection coefficient mean?
A: A positive s indicates the allele is advantageous and will increase in frequency over time.

Q2: What does a negative selection coefficient mean?
A: A negative s indicates the allele is disadvantageous and will decrease in frequency over time.

Q3: What range is valid for initial frequency?
A: F0 must be between 0 and 1 (0% to 100% frequency in the population).

Q4: How does generation time affect the results?
A: More generations allow more time for selection to act, resulting in greater frequency changes.

Q5: When is this model not appropriate?
A: This assumes constant selection pressure, random mating, large population size, and no other evolutionary forces.